Ameliorative Effect of Nigella sativa Oil against Paracetamol Induced Hepatic and Renal Damages in Rats

Hasan, Mohammed Nazer and Khan, Rahat Ali and Nasiruddin, Mohammed and Khan, Aijaz Ahmed (2016) Ameliorative Effect of Nigella sativa Oil against Paracetamol Induced Hepatic and Renal Damages in Rats. British Journal of Pharmaceutical Research, 13 (3). pp. 1-10. ISSN 22312919

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Official URL: https://doi.org/10.9734/BJPR/2016/27597

Abstract

mol (750 mg/kg) only and Group III to IV were test groups treated with Paracetamol (750 mg/kg) and Nigella sativa oil (1 & 2 ml/kg respectively) for 7 days. On 8th day all rats were sacrificed and blood were collected for liver and renal function tests and tissue samples for histo-pathological examination.

Results: Paracetamol caused marked hepatic and renal damages which were prevented by Nigella sativa oil in dose dependent manner.

Conclusion: Nigella sativa oil showed significant hepato- and reno-protection against Paracetamol induced damages.

Item Type:	Article
Subjects:	Lib Research Guardians > Medical Science
Depositing User:	Unnamed user with email support@lib.researchguardians.com
Date Deposited:	05 Jul 2023 05:07
Last Modified:	23 Jan 2024 04:40
URI:	http://journal.edit4journal.com/id/eprint/1224

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